Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines
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چکیده
منابع مشابه
Corrigendum: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines
This corrects the article DOI: 10.1038/sdata.2017.33.
متن کاملTranscriptomic profiling of 39 commonly-used neuroblastoma cell lines
Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease. While many of these cell lines have been previously characterized with SNP, methylation, and/or mRNA expression microarrays, there has not been an effort to comprehensively sequence these cell lines. Here, we present raw whole transcriptome data generated by RNA sequencing of 39 co...
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BACKGROUND Cancer stem cell theory suggests that the presence of tumor initiating stem-like cells in cancers may be responsible for cancer progression and relapse. CD133 cell surface maker expression has been used to identify stem-like cells in cancer cell lines. Our goal was to identify such cells in neuroblastoma cell lines and to study the cytotoxicity of common anticancer drugs for those ce...
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Neuroblastoma is the most common pediatric cancer, arising from the neural crest cells of the sympathetic nervous system. Its most aggressive subtype, characterized by the amplification of the MYCN oncogene, has a dismal prognosis and no effective treatment is available. Understanding the alterations induced by the tumor on the various layers of gene expression is therefore important for a comp...
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ژورنال
عنوان ژورنال: Scientific Data
سال: 2017
ISSN: 2052-4463
DOI: 10.1038/sdata.2017.33